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Sa-079-Regional differences in microvascular regulatory control during ephemeral blood pressure perturbations
Regional cortical differences in dynamic cerebral autoregulation were assessed using functional near-infrared spectroscopy-derived transfer function analysis (TFA) estimates. Thirty-two participants (23 females) completed repeated squat-stand maneuvers at 0.05 and 0.10 Hz with TFA outcome metrics of phase and normalized gain across motor, frontal, dorsolateral prefrontal, somatosensory, and occipital cortices. Multiple linear regressions noted no differences with biological sex or hemisphere; however, a greater normalized gain and greater phase was present in the occipital cortex. These insights enhance the understanding of cerebral blood flow regulation and emphasize the complexity of vascular responses across different brain regions. Continue reading
Su-054-Developing an Inclusive Approach to fNIRS Measurement in Minority Study Participants
Our lab has been working to develop a more inclusive approach to fNIRS measurement in individuals who are typically excluded from fNIRS studies—specifically women of color. We present our approach as well as future work in this area to improve recruitment and retention of women and persons of color in fNIRS studies. Continue reading
Sa-006-Functional Connectivity differences among Children in the Rural Ecuadorian Amazon who Drink Chicha
Chicha is a very common fermented beverage that is used as a nutritional supplement in the Ecuadorian Amazon. Despite the prevalence, the impact of Chicha on cognitive and neural development has not been studied. A 68-channel NIRSport2 montage was used, and a resting-state connectivity analysis will be performed on all channels. Preliminary results indicated a notable lack of connectivity from the medial PFC and higher connectivity in Dorsal regions. We expect connectivity patterns to be moderated by children’s Chicha consumption. Continue reading
Vi-033-fNIRS brain imaging at 1 month of age in the UK and The Gambia – a multi-paradigm approach
At the first fNIRS session of the Brain Imaging for Global Health (BRIGHT) (www.globalfnirs.org) at 1 months of age, we use a multi-paradigm approach while infants sleep, to investigate brain responses during presentation of a range of auditory stimuli. Our preliminary results show that infants developing in the UK and The Gambia (GM) present different response patterns to the same stimuli. We will investigate further these differences by studying the brain networks underpinning these responses from the functional connectivity (FC) data collected in the same sessions, and by incorporating contextual factors into the analysis. Continue reading