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Tag Archives: Other fNIRS Topics
Fr-046-Fronto-parietal cortical activation during balance tasks in children with Developmental Coordination Disorder – Preliminary results
Balance problems are prevalent in children with Developmental Coordination Disorder. However, the underlying brain control mechanisms still need to be unravelled. Cortical activity in the fronto-parietal regions can be investigated during balance tasks with functional Near-Infrared Spectroscopy (fNIRS). This can offer crucial insights to disentangle the origin of the balance difficulties. Four DCD and four TD children performed three balance tasks while undergoing fNIRS. Across participants, an increase of the mean hemodynamic response function relative to the HbO2 concentration was observed at task onset with an opposite trend for the HbR responses. Further analysis with larger sample sizes are needed. Continue reading
Vi-018-Study on improvement of spatial resolution of topography
We propose to use three kinds of source-detector pairs with different distances to improve spatial resolution and reduce artifacts. The simulation results using a depth-selective filter algorithm show that surface signal can be reduced with minimum target signal deterioration, and the use of two different measurement signals allows to detect target signal of different optical transfer path. Continue reading
Su-032-Using fNIRS to Examine Neural Mechanisms of Change Associated with Mindfulness-Based Interventions
Abstract: This study explores the neural mechanisms of change in individuals participating in mindfulness-based interventions (MBI) using functional near-infrared spectroscopy (fNIRS). Data were collected from 17 participants performing tasks designed to measure neuro-cognitive functions, including attentional control, emotional regulation, and working memory. These tasks included Emotional Stroop, Emotional Working Memory, Go/No Go, N-back, and Reaction Time. Eight participants completed an 8-week MBI program, while nine participants were in the control group. Preliminary analyses are ongoing, with complete results expected by summer. This research aims to elucidate the effects of MBIs on cognitive functions through direct neurophysiological measures. Continue reading
Sa-101-Novel fNIRS Digitization Methodology, Firefly: Innovative 3D Imaging and Software
Optode location variance due to cap placement and head topology, as well as scalp-cortex correlation, are essential aspects of fNIRS research. We present an innovative digitization methodology, Firefly (© pending), utilizing blue-light 3D imaging, color-depth mapping, and custom software applications to provide dynamic assessments of optode positioning during capping procedures, compatible with EasyCap and custom probe designs. Pilot data suggest our methodology enhances digitization localization and offers a robust solution to convert channel space locations to voxel space locations within the brain volume; ultimately providing researchers with an efficient, unified solution for creating scalp-cortex sensitivity profiles. Continue reading
Sa-076-A Cloud-Based NIRS Data Pipeline: Application to Wearable Device for Placenta Monitoring
Wearable continuous non-invasive home monitoring of placenta function during pregnancy is an urgent clinical need. While NIR technologies can monitor placenta oxygenation, consideration needs to be given of how these NIR devices can store, process and present the data in a safe, real-time and efficient way. We will outline and demonstrate an AWS based cloud computing pipeline that allows (1) to secure the data from a portable wearable NIRS device that we developed called FetalSense; (2) pre- and post- process the data with real-time quality checks and algorithms to resolve physiological quantities; and (3) display information of clinical value. Continue reading
Sa-086-Influence of Skin in the Estimation of Optical Properties with Frequency-Domain Diffuse Optical Spectroscopy
This study investigated the bias introduced in the optical properties estimated with FD-DOS when skin is ignored. We derived the skin’s absorption coefficient as a function of skin colour and used this relationship to quantify the influence of skin on the absorption coefficient of turbid media. We show that dark skin introduces errors of up to 9% in the absorption coefficient and 4.5% in oxygen saturation. Last, we propose a skin-dependent correction factor to decrease the bias in FD-DOS Continue reading
Vi-012-Investigating Relationship between Reading Speed and Comprehension in English Learners using fNIRS
Abstract: Reading is a complex activity that integrates cognitive, linguistic, and psychological factors. This study explores the relationship between reading speed and comprehension by underlying neural mechanisms using functional near-infrared spectroscopy (fNIRS). Employing block method, 20 MPhil English students (10 M; 10 F) participated in the reading tasks. Initial findings reveal distinct activation patterns in the left hemisphere during reading tasks, highlighting the diverse cognitive functions supported by different cortical regions. These findings offer insights into the neural activation patterns during reading comprehension and correlation between reading speed and comprehension. Continue reading
Fr-054-Diffuse Optical Monitoring of Cytochrome C Oxidase and Hemodynamics during Drug-Induced Mitochondrial Dysfunction in Swine
We integrated broadband and frequency-domain diffuse optical spectroscopy to monitor cerebral oxidized cytochrome-c-oxidase (oxCCO) and oxygen extraction fraction (OEF) during drug-induced mitochondrial dysfunction in swine. Swine infused with rotenone to inhibit mitochondrial Complex I were treated with a novel succinate prodrug or placebo. An invasive microdialysis lactate-pyruvate ratio (LPR) metric of metabolism was also acquired. No changes in oxCCO or OEF were observed in the placebo group. In the treatment group, increased oxCCO and decreased OEF were observed, and these changes correlated with increased LPR. Results suggest oxCCO and OEF are sensitive to mitochondrial impairment during non-ischemic conditions. Continue reading
Fr-055-Effects of Motor Awareness on Peripheral Muscle Blood Flow at the Onset of Exercise
Central command originating from the brain to the skeletal muscles alter the systemic circulatory system to increase blood flow to active muscles. Attention to the active muscles during exercise may lead to improvements in exercise efficiency and performance. However, the hemodynamic effects of directing attention to active muscles are unclear. Using diffuse correlation spectroscopy, we investigated the effect of awareness of active muscles on peripheral hemodynamics. Our results demonstrate that motor awareness significantly increased active muscle blood flow immediately after the onset of exercise. Continue reading
Fr-063-Liquid optical phantoms for use in NIRS: A systematic review
This systematic review explores the use of liquid phantoms in Near-Infrared Spectroscopy (NIRS) instrumentation development. Following the PRISMA methodology from 2018 to 2023, 111 papers were identified and included in the literature review. Most researchers used Intralipid and India ink in their liquid phantoms. Blood phantoms were less common due to many instruments not measuring oxygenation. Instead, most instruments measured the optical properties of the targeted tissue, or changes in said optical properties. When blood was used, human blood was most common, with yeast as the preferred deoxygenation agent. The review highlights the prevalence of liquid phantoms, and emphasizes the need for a standardization process in their development. Continue reading